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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415c8e15c7ede6ba92aa13f8e259ab83f56765e61e135136b96b77b06fcf0728' 
  AND token = 'mcBvfsQgnMi6Wwm77w3wp+b6VBzaIRJsRP3L609JSUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}