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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a562f2480187f850a06039824e8b97cc4ea8850dfee9a5d1df78842e84e7721' 
  AND token = '4BroRQPrhRpkNu5yMc/46shm1by/DDXZKeV3dAwYnHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}