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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9b50340b33de94b29f2aa08c29edf383e9795db9f57c18aa42d52f7b27d02c9' 
  AND token = 'DSj5DEJOh3rsrz056euOkNxmaZDhRf0cj8M0pQhF+S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}