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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec939e40a1448f63f072539d1bed621dbea54aab6b777395db1e297e1eb61a9' 
  AND token = 'd0WOQfyEwoPFSkhxEc60SXbhsIKVOv+bPcyLIiZvrSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}