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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e946db5ebf57f35a26061bfd26dc3d5d08b74751203ec066976e4a3c8ff08d15' 
  AND token = '/iWoTppNhkaX0MpTCFIAplGIE0xraxOMnxFE7AT5ph0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}