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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6203782404be2a88337941517428826b14bac1c631fb9fabb00c94eea01b0422' 
  AND token = 'ya2XBjYsMngkkiWDRZfSySoNEzP4wDXjpPnH9ZV8IvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}