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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7adb458ca0c717a8eab755c390454a4fade662f20a79370df493a8bbfc8a58f' 
  AND token = 'DOMI/I9Z6ISyq5ToV0b/Z/2F4iBVuvUiASrBKuDu314=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}