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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33654dd1e7f6bbb0323504a6de2847a4e60929ba0aeb7f6f536e091d726db148' 
  AND token = 'nvYz8vIDNxZ3G6KD2sZhGTl+5Aedkep//pZ2udShyT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}