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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7f5fe10c53cdf82d81146f5d1393884c50919e4becdb31789ec7d680fa6880' 
  AND token = 'b4W92WkmOsTAg4eX2b2bYyL7DZBi2ceBJr6Po9qa7Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}