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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f79e0b2ec1f8ec47335805626e86c165f9b2e74a780847432b2b6da415e421dd' 
  AND token = 'HkCM+EKeYtllPQI4UZMPbVRJR+DpO6HkM20AHRSYb6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}