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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e245cebd3184fff3ca1b41da97c88670c1106bb8ff0fe82128dd74202762eade' 
  AND token = 'lYY4A2Xblg30YO/MTOsa7lxRkRwDQ2rYycvAvuRXHwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}