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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f2f6638c86036d3f4ab7a261f2ecc6d14b868e00dba4ecd5cd61f382a407e4' 
  AND token = 'ZEspuB/kMqal8W1i4kDS7BDL7V++jx/QlBtXCb+P6/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}