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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8ac1068960d3760d899908cb4cef76420a4289ffbacabe0b0b5f74b0de2f42' 
  AND token = 'uD8izb/YuBEzLBT/+OvKFmIEwY5Q1D97RPH8M75zHZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}