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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c0ecc72c80649a17efb3c1afe27a10d35bf9742e48041999420986cbd87afd' 
  AND token = 'MfAMr1gW9WJ+JHS7iYpv3/dzrrDUK6YkbK7j2g0/ucU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}