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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d501e53e560597b88a87ded09d50e28386fd16e6feab82b86d7e52904392011' 
  AND token = 'U0a6ni/2x7D66dWxRsMW2pRwS+jkci6AF0zuWlamAOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}