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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a89a0995ad6f2619a4aa772d97893987a1929b4240f559d041c9479dec8bd6e8' 
  AND token = 'IGp/oKn0evM/NrN3xv5HrhMXH3MUr8OKEWgs/Lfouls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}