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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a5ee0ec21a11df5d090ca11508a8cd554e075fe4dd02c1e07f432ea21edb68' 
  AND token = 'E8d5u1I2AZFbSvzYnrTqtvuvY8fz9yyWr8brOKXp2Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}