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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d75ce74f2300b3d8a4a5174102599a075e878267593b7ce322fb58d1ba4d5a4' 
  AND token = 'ab+Wld02/VTqZVDtXWEFOMl9T0hba5rpMGVXMgi4YY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}