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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35fb17d4e2d18990f8d91a989b70172d14516f6de25f848d54966027083fa8b0' 
  AND token = 'kbg3bbg3bfbg1tPyRNnRtawa6jnULYfusSUwVZ5ewsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}