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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab73a179311ac05bc362cde2bd856b7f2e77b17b8388de22e81bf0fd52e1f78' 
  AND token = 'mhCLYdgsOvTUpi+utiMu+ITTmIr+tTfp1RqWMfdqdms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}