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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb741637953ad5d3c1fbeee6125d5c0722c6b4498042c641bd9eeeb3b6ef366' 
  AND token = 'vwPpidRZpDPK/b/DMOYCjKW4QzcXf4xfsksSTEfgzJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}