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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4645ce26c7d6156b4ff5a23d6db98218cda2325ee5acae8448cf1c61ae1d1642' 
  AND token = 'H4+OYFvb3QbOu9Duz/lo//XzpYQEiHaSQ+IrYWJgKMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}