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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de1160a50f4d048c6eae3c0af1f3aa7a437f8d222ccbf54f58783cc1eb37995' 
  AND token = 'ZGYY3wH4IumEBl9igY4Kk8uS6H72/E3/pSKvyjEh1Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}