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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c32261b9148689ac49ee5f1449e75ce7782edad67a032cd0f2e4281e34efd04' 
  AND token = 'JmxoW+oO0QwJ6xlgjj2/WnDhI1+scxT2G8db/+XTQ1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}