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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a3e98d1937663a4f852bf15b2d575f2f3baeac954b5a8644fddd30004a9045' 
  AND token = 'y3zHo0oAJXeiAOytg3n2syxxiV37EPpdr4p5FXYZGe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}