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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2a9de4fcf22bff25eddd514bb27ca357eb51586e6d2a0a3ee0d1b5f1f5a26f' 
  AND token = '7RG7K0CDwqdFbBR90jEPJTN//w97QTlE33vnJm4bGwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}