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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdddbc3ee44feaed552d664ebca13588f5e161f8d3ebf53bd80fb84df2e39501' 
  AND token = 'vMidM1wG0D6M26sJTwKn9GcOl2nXR/ZpW5jgC9m3m60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}