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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508f9161cbe8956c3d71333b30733bbba8147d83ac73e81d2fbb6f21e9e219e9' 
  AND token = 'UW5PEwb2ortsduxrPiQ8zE8rAtULNaXQuAbIdks23nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}