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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47e1e8edda20b17a7453f71f420a8d2f29205e1a2d2fa7ebed6ebd81aeb0739f' 
  AND token = '05tusr0kBMq1XrQuvmchIYeimSjTwHiy9tY+MdXfmCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}