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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a389221dec5f3877ff4123bb4891d9fabdd66c4d4e2eb3dee0606a364f0ecdb' 
  AND token = 'A1u/z1N29xMmNb32A/jzUXuvpQNCS11IhuBIehc89Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}