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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ab22d26a06d0757f1cc2738f0de432665083194db2dc5e99271f4f55ee9d763' 
  AND token = 'rFeeRtQ7Abrv4H20Lr6BOSUugrg9fKqW0IV646iQQX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}