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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4294f031dc41ff2481e3f8f9e27784a8b3fcb8cdcd94afbb366d484554e76ad' 
  AND token = 'DvdvaAF1+IaqBVj+9k/as+kiBAvTSoeeL63Z91uzhE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}