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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8522e87ff54be1aa00a25071af668b6f978aed1b560a6005add8d189ab6e6191' 
  AND token = 'IFYUhuHd79RKxKaZA4QIwjIj/NdVELBS9PWZCKcgWT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}