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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffb332e4364db92ce3c409b942bee30b28da047e8f57dcd384c0c9d00415779' 
  AND token = 'QSVWcrJJLFcWcuxm+wMkNELeNNxEzWpYNCYmwsDYoG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}