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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df41e2a67ae51be1e64a2192a9d3c056ccc53f3a2f63e16440d369881ac8783' 
  AND token = 'K5dSF+vb6myTWqKOzJ++LkFa3CsHpFVQKQgCT7CN8yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}