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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420d68450328ee4f47c3560ad07c633343db6f20f6a60c9d8603538d1d2db9ce' 
  AND token = '3//nF+QMyX/wf+pHb8a4+Oc1n3bxAPkUiRfcDs4KcyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}