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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4166a7b1b6991c183e1b488e100b8935f96398748b16ee18df964c40f9ae12' 
  AND token = 'T8nCH5Rp2NYz+F89QeIApMgYGauY1u+giR1gjukNp1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}