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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fa0e2faa7f4f174d1465903439cdffff4863d16d863f206d0d282743a548f0' 
  AND token = '52CQdKxsJ2ooRwSqFkKZTIvZGaOy5d5r2Fs9Y/aHzBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}