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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe33d1b2bdf2f13932ab7d25f28953c34a9e0734a23fba0c2ef779e15d826ce' 
  AND token = 'tqmBBThMdo3rGTcmq3HOSYW3ZKHCWxCMqzICPtkN3e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}