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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efac5be180f4d2e1140ac665b4fb544d94b2ccb474f8fe5264de2e2ed6dded34' 
  AND token = 'ANRe8sSsjouFpVLnV5PyjNW1/tJsf4H6bYlox1WdtsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}