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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db5bbfc5ca2731f8523c30277d67df92d81895fd3637c3acfe65f72ab8c2b00' 
  AND token = 'HnA/VKmb1NGSZB43EilEKubeMAAnmKKgHExa2AN/RYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}