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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151d421a597eb07a106663debe9e9da36ecf2abdf37f94acab35f62810a9deff' 
  AND token = 'kaMMRyUvBqz7SBoNt5Qin3rKBG95Ap//OUOJtnwoBvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}