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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7a24c3f7013e8c6480f841284b33386c80211ecf03159a1dbbe506c4c5dac9' 
  AND token = 'xYClS9d9IWhB00xHBkPIIq7ovVcm6ZXL6GIECVpMEI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}