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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89b3c234ecda711c1bc0ac0bd57eb3c7bd5f781809837239ec899f1c66f50c9' 
  AND token = 'qn7kj1cpViAOoFzX/eOIGxUAHi+Ybc45hoycKa8LFsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}