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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39790876c77375be1ecc9c1c925039e36df44b41ab0f01650fff1c7b7bc17b5' 
  AND token = 's7cTA9jCAlBUg6vnVF+2ObWiVajF8WYm7D6nnW8S/9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}