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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6144d9f78b0c5008ecec33ae3e61fb2d305062ff8e628c0f6baff9a2a70ffe5e' 
  AND token = 'nq1b3ub8f32mxgo1JcK9hUwScSbAkhEm6eszaFkUnsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}