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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8025cebd1ed46b0d599a9649f2590abbf945ffb5859f33e60da6ffd5d89b3cea' 
  AND token = 'VJcEViIXx11/+LMLWjeChtDcPmf8ef738KdBEPL0Uxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}