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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be2a0e33fa41e3500664a0c359e79ffb43d14ba8c4c0d304b2f028bde0f71cb' 
  AND token = 'fxTO60sYVdIkZWg0RJHKZP8ZOaGWP89WeDnjs5burUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}