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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58540e74511c6c550169ad9bc207dc25ee4865cfb5de3beea634ce3856a38bf5' 
  AND token = 'h2VqfHy1Hv8vm2Hdu3b5TjM6Qdg+OTI7ywJ3oVsf0p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}