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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f346d68fad4973482edd0decba7fe69cd48e56605664ce1c1bde0c6e7d613e1b' 
  AND token = 'NpS93MPs6OsbiN6m/NFa4WwxjyPHYEN+UTPFIFcqaSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}